Lhermitte-Duclos Disease: Literature Review and Novel Treatment Strategy
نویسندگان
چکیده
منابع مشابه
Lhermitte - duclos Disease :
Lhermitte-Duclos disease (LDD) is a benign neoplasm of posterior fossa, involving cerebellum. It is also known as dysplastic cerebellar gangliocytoma. It is not a true neoplasm but a hamartoma. It can be either isolated finding or associated with Cowden (multiple hamartoma syndrome). adults.
متن کاملLhermitte-Duclos disease.
Lhermitte-Duclos disease was first described in 1920 in the literature under the names of Purkinjeoma, granular cell hypertrophy of the cerebellum, hamartoma of the cerebellum, dysplastic gangliocytoma, ganglioneuroma, and gangliomatosis of the cerebellum. Patients tend to be young adults and may present with signs of cerebellar dysfunction or increased intracranial pressure secondary to obstru...
متن کاملLhermitte-Duclos disease.
Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) is a rare benign cerebellar mass of unknown etiology which is characterized by enlargement of the cerebellar folia. Despite the controversy regarding its pathogenesis, imaging and histopathological findings are rather typical. A 17-year-old female presented with a 2-year history of progressive headaches and gait imbalance. Cr...
متن کاملSuccessful Treatment of a Patient with Lhermitte-Duclos Disease (a Case Report and Literature Review)
Lhermitte-Duclos disease, also known as dysplastic cerebellar gangliocytoma, was first diagnosed by doctors Lhermitte and Duclos in 1920. In subsequent years, the disease was described by many researchers: Bielschowsky and Simons in 1930, Christensen in 1937, Duncan and Snodgrass in 1943, Ambler in 1969, and Padber in 1991. Each of the authors referred to this disease in a different way: diffus...
متن کاملLhermitte-Duclos disease and pregnancy
Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) is a rare disorder, characterized by a slowly progressive unilateral neoplastic mass of the cerebellar cortex. The histopathological findings of LhermitteDuclos disease (LDD) include the widening of the molecular layer, which is occupied by abnormal ganglion cells, absence of the Purkinje cell layer and hypertrophy of the granulan c...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1997
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s031716710002151x